Hamas health officials say at least 110 Palestinians have been killed in Israeli airstrikes in Jabalia in northern Gaza.
There's been no specific comment from Israel, which insists it is targeting what it calls terrorist infrastructure.
Jabalia, part of which is a long-standing refugee camp, is in the north of Gaza - an area where, since the early days of the war, Israel has warned people to leave.
US Secretary of Defence Lloyd Austin is meeting Israeli officials today, as the UK, France and Germany step up global calls for a ceasefire
At the UN Security Council, the US is said to be seeking to tone down the words of a new draft resolution calling for a cessation of hostilities.
Hamas broke through Israel's heavily guarded perimeter on 7 October, killing 1,200 people and taking 240 hostages - some of whom were released during a brief truce.
The health ministry in Gaza, which is run by Hamas, says more than 19,400 people have been killed and 52,000 injured in the enclave since the start of the Gaza war.